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Week 10 Early Afternoon Games
Houston Texans (4-4) 2nd AFC South @ Cincinnati Bengals (5-3) 4th AFC North
- Where: Paycor Stadium, Cincinnati, Ohio
- When: 1:00 PM EST
- TV: CBS
- Line: Cincinnati Bengals -6.5
- Over/Under: 47
New Orleans Saints (5-4) 1st NFC South @ Minnesota Vikings (5-4) 2nd NFC North
- Where: U.S. Bank Stadium, Minneapolis, Minnesota
- When: 1:00 PM EST
- TV: FOX
- Line: New Orleans Saints -3
- Over/Under: 41
Green Bay Packers (3-5) 3rd NFC North @ Pittsburgh Steelers (5-3) 2nd AFC North
- Where: Acrisure Stadium, Pittsburgh, Pennsylvania
- When: 1:00 PM EST
- TV: CBS
- Line: Pittsburgh Steelers -3
- Over/Under: 39
Tennessee Titans (3-5) 4th AFC South @ Tampa Bay Buccaneers (3-5) 3rd NFC South
- Where: Raymond James Stadium, Tampa, Florida
- When: 1:00 PM EST
- TV: CBS
- Line: Indianapolis Colts -2.5Tampa Bay Buccaneers -1
- Over/Under: 39.5
San Francisco 49ers (5-3) 1st NFC West @ Jacksonville Jaguars (6-2) 1st AFC South
- Where: EverBank Stadium, Jacksonville, Florida
- When: 1:00 PM EST
- TV: FOX
- Line: San Francisco 49ers -3
- Over/Under: 45
Cleveland Browns (5-3) 3rd AFC North @ Baltimore Ravens (7-2) 1st AFC North
- Where: M&T Bank Stadium, Baltimore, Maryland
- When: 1:00 PM EST
- TV: FOX
- Line: Baltimore Ravens -6.5
- Over/Under: 38